Invitrogen™ INHBB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598319

Catalog No. PIPA598319

Description

INHBB Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Specifications

• Antigen: INHBB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INHBB
• Gene Alias: activin AB beta polypeptide; activin betaB; activin beta-B chain; INHBB; Inhibin beta B chain; inhibin beta B subunit; inhibin beta subunit B; inhibin beta-B; inhibin, beta B; Inhibin, beta-2
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3625
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P09529
• Gene Symbols: INHBB
• Immunogen: Recombinant Human Inhibin beta B chain protein (295-405AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG