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Invitrogen™ INHBB Polyclonal Antibody
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Catalog No. PIPA5119792
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100 μL
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PIPA5119792 100 μL
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Catalog No. PIPA5119792 Supplier Invitrogen™ Supplier No. PA5119792
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Description

Rabbit Polyclonal Antibody

Positive Control: SK-Br-3 cell lysate, MCF-7 cell lysate, human uterus tissue, mouse brain tissue. Subcellular Location: Secreted.

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INHBB
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene INHBB
Gene Accession No. P09529, Q04999
Gene Alias activin AB beta polypeptide; activin betaB; activin beta-B chain; INHBB; Inhibin beta B chain; inhibin beta B subunit; inhibin beta subunit B; inhibin beta-B; inhibin, beta B; Inhibin, beta-2
Gene Symbols INHBB
Host Species Rabbit
Immunogen Synthetic peptide within human Inhibin beta B aa 345-380.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16324, 3625
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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