Invitrogen™ INHBB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550818

Catalog No. PA550818

Description

The antibody detects endogenous levels of total INHBB protein.

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Specifications

• Antigen: INHBB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INHBB
• Gene Alias: activin AB beta polypeptide; activin betaB; activin beta-B chain; INHBB; Inhibin beta B chain; inhibin beta B subunit; inhibin beta subunit B; inhibin beta-B; inhibin, beta B; Inhibin, beta-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16324, 25196, 3625
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 2.9 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P09529, P17491, Q04999
• Gene Symbols: INHBB
• Immunogen: Synthetic peptide of human inhibin, beta B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG