Invitrogen™ INO80 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140070

Catalog No. PIPA5140070

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: KRQQRKLNFL ITQTELYAHF MSRKRDMGHD GIQEEILRKL EDSSTQRQID IGGGVVVNIT QEDYDSNHFK AQALKNAENA YHIHQARTRS FDEDAKESR.

DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.

Specifications

• Antigen: INO80
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ino80
• Gene Alias: 2310079N15Rik; 4632409L19Rik; Chromatin-remodeling ATPase INO80; DNA helicase INO80; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; hINO80; homolog of yeast INO80; Ino80; INO80 complex homolog 1; INO80 complex subunit; INO80 complex subunit A; INO80 homolog; INO80 homolog (S. cerevisiae); INO80A; Inoc1; KIAA1259; putative DNA helicase INO80 complex homolog 1; RGD1310969; yeast INO80-like protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54617
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9ULG1
• Gene Symbols: Ino80
• Immunogen: Recombinant protein corresponding to Human INO80.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG