Invitrogen™ INPP5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522231

Catalog No. PIPA522231

Description

Recommended positive controls: H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (87%), Rat (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: INPP5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5B
• Gene Alias: 5PTase; 75 kDa inositol polyphosphate-5-phosphatase; AW260155; inositol polyphosphate-5-phosphatase B; inositol polyphosphate-5-phosphatase, 75kDa; INPP5B; INPP5P; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; MGC65156; MGC71303; OCRL2; Phosphoinositide 5-phosphatase; RP11-109P14.7; type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol 1,4,5-trisphosphate 5-phosphatase; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol-1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3633
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.34 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P32019
• Gene Symbols: INPP5B
• Immunogen: Recombinant fragment corresponding to a region within amino acids 699 and 949 of INPP5B (Uniprot ID#P32019).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG