Invitrogen™ INPP5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544211

Catalog No. PIPA544211

Description

Peptide sequence: IHNGQVPCHF EFINKPDEES YCKQWLNANP SRGFLLPDSD VEIDLELFVN Sequence homology: Dog: 85%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 77%; Rat: 92%.

Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: INPP5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5B
• Gene Alias: 5PTase; 75 kDa inositol polyphosphate-5-phosphatase; AW260155; inositol polyphosphate-5-phosphatase B; inositol polyphosphate-5-phosphatase, 75kDa; INPP5B; INPP5P; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; MGC65156; MGC71303; OCRL2; Phosphoinositide 5-phosphatase; RP11-109P14.7; type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol 1,4,5-trisphosphate 5-phosphatase; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3633
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P32019
• Gene Symbols: INPP5B
• Immunogen: Synthetic peptide directed towards the middle region of human INPP5B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov