Invitrogen™ INPP5J Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532876

Catalog No. PIPA532876

Description

Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (87%); Marmoset (80%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transductions from growth factors, neurotransmitters and G protein coupled receptors. INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP (proline-rich inositol polyphosphate 5-phosphatase), PIB5PA or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate. Expressed in lung, stomach, kidney, brain, small intestine and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins. Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.

Specifications

• Antigen: INPP5J
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5J
• Gene Alias: Inositol polyphosphate 5-phosphatase J; inositol polyphosphate-5-phosphatase J; Inpp; INPP5; Inpp5j; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Pib5pa; Pipp; Proline-rich inositol polyphosphate 5-phosphatase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27124
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q15735
• Gene Symbols: INPP5J
• Immunogen: Synthetic 15 amino acid peptide from N-terminus of human INPP5J / PIB5PA.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG