Invitrogen™ INPP5J Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104005

Catalog No. PIPA5104005

Description

Antibody detects endogenous levels of total INPP5J.

Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transductions from growth factors, neurotransmitters and G protein coupled receptors. INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP (proline-rich inositol polyphosphate 5-phosphatase), PIB5PA or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate. Expressed in lung, stomach, kidney, brain, small intestine and heart, INPP5J localizes to membrane ruffles, where it may also participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins. Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.

Specifications

• Antigen: INPP5J
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INPP5J
• Gene Alias: Inositol polyphosphate 5-phosphatase J; inositol polyphosphate-5-phosphatase J; Inpp; INPP5; Inpp5j; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; Pib5pa; Pipp; Proline-rich inositol polyphosphate 5-phosphatase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171088, 27124
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q15735, Q9JMC1
• Gene Symbols: INPP5J
• Immunogen: A synthesized peptide derived from human INPP5J(Accession Q15735), corresponding to amino acid residues G946-H996.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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