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Invitrogen™ INSIG1 Polyclonal Antibody
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Catalog No. PIPA541706
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100 μL
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Catalog No. Quantity
PIPA541706 100 μL
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Catalog No. PIPA541706 Supplier Invitrogen™ Supplier No. PA541706
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Description

Rabbit Polyclonal Antibody

Peptide sequence: ITIAFLATLI TQFLVYNGVY QYTSPDFLYI RSWLPCIFFS GGVTVGNIGR Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%.

Oxysterols regulate cholesterol homeostasis through liver X receptor (LXR) and sterol regulatory element-binding protein (SREBP) mediated signaling pathway. This gene is an insulin-induced gene. It encodes an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. This protein binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INSIG1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene INSIG1
Gene Accession No. O15503
Gene Alias 1810013C12Rik; CL6; CL-6; fb55a03; fi35b10; growth response protein (CL-6); immediate-early protein CL-6; INSIG1; INSIG-1; INSIG-1 membrane protein; insulin induced gene 1; insulin induced protein 1; insulin-induced gene 1 protein; Insulin-induced growth response protein CL-6; MGC1405; wu:fb55a03; wu:fi35b10; zgc:55439
Gene Symbols INSIG1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human INSIG1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3638
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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