Invitrogen™ INSIG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103441

Catalog No. PIPA5103441

Description

Antibody detects endogenous levels of total INSIG2.

INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Specifications

• Antigen: INSIG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INSIG2
• Gene Alias: 2900053I11Rik; C730043J18Rik; Insig2; INSIG-2; INSIG2 membrane protein; INSIG-2 membrane protein; insulin induced factor 2; insulin induced gene 2; insulin induced protein 2; insulin-induced 2 protein; insulin-induced gene 2 protein; insulin-induced membrane protein 2; MGC26273
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 288985, 51141, 72999
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q80UA9, Q91WG1, Q9Y5U4
• Gene Symbols: INSIG2
• Immunogen: A synthesized peptide derived from human INSIG2(Accession Q9Y5U4), corresponding to amino acid residues M1-V45.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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