Invitrogen™ INSL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588926

Catalog No. PIPA588926

Description

Immunogen sequence: MASLFRSYLP AIWLLLSQLL RESLAAELRG CGPRFGKHLL SYCPMPEKTF TTTPGGWLLE SGRPKEMVST SNNKDGQALG TTSEFIPNLS PELKKPLSEG QPSLKKIILS RKKRSGRHRF DPFCCEVICD DGTSVKLCT; Positive Samples: Rat lung.

Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Insulin-like peptides (INSL proteins), also designated Relaxinlike factors, are members of the insulin family, which regulate cell growth, metabolism and tissue-specific functions. INSL1-7 are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. INSL4 is a 139 amino acid secreted protein expressed in the placenta, uterus and in fetal perichondrium. It may play an important role in the regulation of bone formation and in trophoblast development.

Specifications

• Antigen: INSL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: early placenta insulin-like peptide; early placenta insulin-like peptide (EPIL); Early placenta insulin-like peptide A chain; Early placenta insulin-like peptide B chain; EPIL; INSL4; insulin like 4; insulin-like 4 (placenta); insulin-like peptide 4; Placentin
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-139 of human INSL4 (NP_0021861).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4.56 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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