Invitrogen™ INSL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106660

Catalog No. PIPA5106660

Description

Antibody detects endogenous levels of total INSL4.

Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Insulin-like peptides (INSL proteins), also designated Relaxinlike factors, are members of the insulin family, which regulate cell growth, metabolism and tissue-specific functions. INSL1-7 are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. INSL4 is a 139 amino acid secreted protein expressed in the placenta, uterus and in fetal perichondrium. It may play an important role in the regulation of bone formation and in trophoblast development.

Specifications

• Antigen: INSL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INSL4
• Gene Alias: early placenta insulin-like peptide; early placenta insulin-like peptide (EPIL); Early placenta insulin-like peptide A chain; Early placenta insulin-like peptide B chain; EPIL; INSL4; insulin like 4; insulin-like 4 (placenta); insulin-like peptide 4; Placentin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3641
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14641
• Gene Symbols: INSL4
• Immunogen: A synthesized peptide derived from human INSL4(Accession Q14641), corresponding to amino acid residues K48-S98.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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