Invitrogen™ INSL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536452

Catalog No. PIPA536452

Description

This antibody detects endogenous protein at a molecular weight of 19 kDa. Purity is >95% by SDS-PAGE.

Insulin is a secreted peptide hormone that elicits metabolic effects such as increases in glucose uptake and glycogen synthesis leading to a decrease in blood glucose concentration. Insulin is first formed as a precursor molecule, preproinsulin, which is later cleaved to proinsulin and finally to the mature insulin hormone. Insulin-like peptides (INSL proteins), also designated Relaxinlike factors, are members of the insulin family, which regulate cell growth, metabolism and tissue-specific functions. INSL1-7 are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. INSL4 is a 139 amino acid secreted protein expressed in the placenta, uterus and in fetal perichondrium. It may play an important role in the regulation of bone formation and in trophoblast development.

Specifications

• Antigen: INSL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INSL4
• Gene Alias: early placenta insulin-like peptide; early placenta insulin-like peptide (EPIL); Early placenta insulin-like peptide A chain; Early placenta insulin-like peptide B chain; EPIL; INSL4; insulin like 4; insulin-like 4 (placenta); insulin-like peptide 4; Placentin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3641
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14641
• Gene Symbols: INSL4
• Immunogen: Synthetic peptide corresponding to amino acids 34-96 of human INSL4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov