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Invitrogen™ INSR Monoclonal Antibody (CT-3)

Catalog No. PIMA513783
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500 μL
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Catalog No. Quantity
PIMA513783 500 μL
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Catalog No. PIMA513783 Supplier Invitrogen™ Supplier No. MA513783

Description

Mouse Monoclonal Antibody

MA5-13783 targets Insulin Receptor beta in ELISA, ICC/IF, IHC (P), Affinity Purification, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-13783 immunogen is recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor.

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INSR
Applications Affinity Purification, ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CT-3
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene INSR
Gene Accession No. P06213, P15208
Gene Alias 4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Gene Symbols INSR
Host Species Mouse
Immunogen Recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor.
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16337, 3643
Target Species Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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