Invitrogen™ INSR Monoclonal Antibody (CT-3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA513783

Catalog No. PIMA513783

Description

MA5-13783 targets Insulin Receptor beta in ELISA, ICC/IF, IHC (P), Affinity Purification, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-13783 immunogen is recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor.

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.

Specifications

• Antigen: INSR
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P06213, P15208
• Gene Symbols: INSR
• Immunogen: Recombinant-fragment including the C-terminal 100 amino acids of human insulin receptor.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Affinity Purification, ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: CT-3
• Conjugate: Unconjugated
• Gene: INSR
• Gene Alias: 4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 16337, 3643
• Content And Storage: 4°C
• Form: Liquid