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Invitrogen™ INSR Polyclonal Antibody
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Catalog No. PIPA5115426
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100 μL
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PIPA5115426 100 μL
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Catalog No. PIPA5115426 Supplier Invitrogen™ Supplier No. PA5115426
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IR.

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INSR
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene INSR
Gene Accession No. P06213
Gene Alias 4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Gene Symbols INSR
Host Species Rabbit
Immunogen A synthesized peptide derived from human INSR(Accession P06213), corresponding to amino acid residues L1329-S1379.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3643
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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