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Invitrogen™ INSR Polyclonal Antibody
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Catalog No. PIPA527334
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100 μL
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PIPA527334 100 μL
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Catalog No. PIPA527334 Supplier Invitrogen™ Supplier No. PA527334
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, NIH-3T3, PC-12, rat liver. Predicted reactivity: Mouse (95%), Rat (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INSR
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.34 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene INSR
Gene Accession No. P06213, P15127, P15208
Gene Alias 4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Gene Symbols INSR
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Intracellular domain of human Insulin Receptor beta. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16337, 24954, 3643
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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