Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA587344

INSR Polyclonal Antibody, Invitrogen™

Catalog No. PIPA587344
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA587344 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA587344 Supplier Thermo Scientific Supplier No. PA587344

Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein Immunogen sequence: PPTLQEMIQM AAEIADGMAY LNAKKFVHRD LAARNCMVAH DFTVKIGDFG MTRDIYETDY YRKGGKGLLP VRWMAPESLK DGVFTTSSDM WSFGVVLWEI T

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen INSR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene INSR
Gene Accession No. P15127, P15208
Gene Alias 4932439J01Rik, CD 220, CD220, CD220 antigen, CD220 beta, CD221, D630014A15Rik, HHF 5, HHF5, IGF-I receptor, INSR, Insulin receptor, insulin receptor preproprotein, Insulin receptor subunit alpha, Insulin receptor subunit beta, IR, IR 1, IR beta, IR1, IR-1, IR-A, IR-B
Gene Symbols INSR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1130-1230 of human Insulin Receptor (NP_0001992)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16337, 24954
Target Species Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.