INSR Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-2885	Proteintech Group Inc 204331AP150UL	150 μL

Description

The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.

Specifications

• Antigen: INSR
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P06213
• Gene ID (Entrez): 3643
• Immunogen: INSR Fusion Protein Ag13922
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: INSR

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CD220, HHF5, INSR, insulin receptor, IR
• Gene Symbols: INSR
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody