Invitrogen™ INSRR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120068

Catalog No. PIPA5120068

Description

Positive test controls include: Mouse brain, Mouse liver, Mouse kidney, Rat kidney. The target is usually found in the following locations: Membrane, Single-pass type I membrane protein. Immunogen sequence: AAGPLRLGGN SSDFEIQEDK VPRERAVLSG LRHFTEYRID IHACNHAAHT VGCSAATFVF ARTMPHREAD GIPGKVAWEA SSKNSVLLRW LEPPDPNGLI LKYEIKYRRL GEEATVLCVS RLRYAKFGGV HLALLPPGNY SARVRATSLA GNGSWTDSVA FYILGPEEED AGGLH.

INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Specifications

• Antigen: INSRR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Insrr
• Gene Alias: Insrr; insulin receptor related receptor; insulin receptor-related protein; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IRR; IR-related receptor; Sirr
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23920, 60663
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q64716, Q9WTL4
• Gene Symbols: Insrr
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 747-921 of human INSRR (NP_055030.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG