Insulin Antibody (2D11-H5 (same as INS05)), Alexa Fluor™ 750, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233146AF750

Catalog No. NP233146A70

Description

Insulin Monoclonal specifically detects Insulin in Human, Mouse, Porcine, Bovine samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Insulin
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: INS
• Immunogen: Purified pig insulin, conjugated to KLH (Uniprot: P01308)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: 2D11-H5 (same as INS05)
• Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Diabetes Research, Immune System Diseases, Immunology, Lipid and Metabolism, Stem Cell Markers
• Gene ID (Entrez): 3630.0
• Target Species: Human, Mouse
• Isotype: IgG1 κ