Insulin Antibody (IRDN/805), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2451090.1MG

Catalog No. NBP24510901

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Insulin Monoclonal specifically detects Insulin in Human, Mouse, Porcine, Bovine, Rabbit, Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Insulin
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
• Gene Accession No.: P01308
• Gene Symbols: INS
• Immunogen: Recombinant INS protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: IRDN/805
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
• Host Species: Mouse
• Molecular Weight of Antigen: 6 kDa
• Quantity: 0.1 mg
• Research Discipline: Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers
• Gene ID (Entrez): 3630
• Target Species: Human, Mouse, Pig, Primate, Rabbit, Rat (Negative)
• Form: Purified

For Research Use Only