Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ INT 131

Tocris Bioscience™ INT 131
GREENER_CHOICE

Catalog No. 742310
Change view
Click to view available options
Quantity:
10 mg
50 mg
Catalog No. Quantity
74-231-0 10 mg
74-235-0 50 mg
2 options
This item is not returnable. View return policy

Catalog No. 74-231-0

Supplier: Tocris Bioscience™ 7423/10

Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

PPARγ partial agonist

INT 131 is a potent and selective PPARγ partial agonist (EC50 = 4 nM; Ki = 3.7 nM). It has a 20-fold higher affinity for PPARγ compared with that of Rosiglitazone (Cat. No. 5325). INT 131 improves glucose tolerance in a rodent model of diabetes without inducing hemodynamic and cardiovascular effects. Antidiabetic agent.

Specifications

Chemical Name or Material 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
CAS 315224-26-1
Quantity 10 mg
Target PPAR gamma/NR1C3
Molecular Formula C21H12Cl4N2O3S
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.