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Tocris Bioscience™ INT 131

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Quantity:
10 mg
50 mg
Description
INT 131 is a potent and selective PPARγ partial agonist (EC50 = 4 nM; Ki = 3.7 nM). It has a 20-fold higher affinity for PPARγ compared with that of Rosiglitazone (Cat. No. 5325). INT 131 improves glucose tolerance in a rodent model of diabetes without inducing hemodynamic and cardiovascular effects. Antidiabetic agent.
Specifications
Specifications
Chemical Name or Material | 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide |
CAS | 315224-26-1 |
Quantity | 50 mg |
Target | PPAR gamma/NR1C3 |
Molecular Formula | C21H12Cl4N2O3S |
Purity | 0.98 |
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