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Integrin Alp v Bta 5 Mouse, anti-Human, R718, Clone: ALULA, BD OptiBuild™

Catalog No. BDB751738 Shop All BD Biosciences Products
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BDB751738 50 μg
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Catalog No. BDB751738 Supplier BD Biosciences Supplier No. 751738
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Description

Mouse Monoclonal Antibody

The ALULA monoclonal antibody specifically binds to Integrin alpha v beta 5 (αvβ5), which is also known as CD51/β5. Integrin αvβ5 is widely expressed by fibroblasts, endothelial cells, and vascular smooth muscle cells. It is involved in activation-dependent cell migration and cell adhesion to the extracellular matrix. Integrin αvβ5 plays a major role in growth factor-induced angiogenesis in response to VEGF and TGF. The αv Integrins, αvβ5 and αvβ3, αre involved in tumor growth and are being targeted in cancer therapies. The ALULA clone specifically recognizes αvβ5 integrin and functionally blocks the interaction between αvβ5 and vitronectin. Although raised against mouse αvβ5, the ALULA antibody crossreacts with human αvβ5.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Integrin Alp v Bta 5
Applications Flow Cytometry
Classification Monoclonal
Clone ALULA
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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