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Integrin alpha 1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Rabbit Polyclonal Antibody

Supplier:  Bioss BS2095R

Encompass_Preferred

Catalog No. 50-198-4513


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Description

Description

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Specifications

Specifications

Integrin alpha 1
Polyclonal
Unconjugated
Itga1
CD49 antigen-like family member A; CD49a; E130012M19Rik; integrin alpha 1; Integrin alpha-1; integrin subunit alpha 1; integrin, alpha 1; ITGA1; Laminin and collagen receptor; very late activation protein 1; Vla1; VLA-1
Rabbit
Protein A
RUO
3672
-20°C
Liquid
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P56199
Itga1
KLH conjugated synthetic peptide derived from human Integrin alpha 1.
100 μL
Primary
Human
Antibody
IgG
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