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Integrin beta 3/CD61 Antibody (Y2/51), Allophycocyanin/Cy7, Novus Biologicals™
SDP

Catalog No. N254418APC7 Shop All R&D Systems Products
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N254418APC7 0.1 mL
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Catalog No. N254418APC7 Supplier Novus Biologicals Supplier No. NBP254418APCCY7
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Description

Mouse Monoclonal Antibody

Integrin beta 3/CD61 Monoclonal specifically detects Integrin beta 3/CD61 in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen Integrin beta 3/CD61
Applications Flow Cytometry
Classification Monoclonal
Clone Y2/51
Conjugate APC-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa
Gene Symbols ITGB3
Host Species Mouse
Immunogen Phytohemagglutinin (PHA)-stimulated peripheral blood cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Cytoskeleton Markers, Phospho Specific, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 3690.0
Test Specificity Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
Target Species Human
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1 κ
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