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Integrin beta-4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501733571 Shop All Proteintech Group Inc Products
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50-173-3571 150 μL
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Catalog No. 50-173-3571 Supplier Proteintech Group Inc Supplier No. 217381AP150UL
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Description

Rabbit Polyclonal Antibody

Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.

Specifications

Antigen Integrin beta-4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ITGB4
Gene Accession No. A2A863, P16144, Q64632
Gene Alias CD104, GP150, Integrin beta 4, integrin, beta 4, ITGB4
Gene Symbols ITGB4
Host Species Rabbit
Immunogen Integrin beta-4 Fusion Protein Ag16450
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192897, 25724, 3691
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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