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Invitrogen™ Integrin beta 7 Monoclonal Antibody (4C5D2)
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Catalog No. FERMA548517
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100 μg
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Catalog No. Quantity
FERMA548517 100 μg
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Catalog No. FERMA548517 Supplier Invitrogen™ Supplier No. MA548517
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Description

Mouse Monoclonal Antibody

Integrin beta 7 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow, ELISA

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Integrin beta 7
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4C5D2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene ITGB7
Gene Accession No. P26010
Gene Alias Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen
Gene Symbols ITGB7
Host Species Mouse
Immunogen Purified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3695
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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