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  6. Invitrogen™ Interferon alpha-2 Monoclonal Antibody (D4), Invitrogen™

Invitrogen™ Interferon alpha-2 Monoclonal Antibody (D4), Invitrogen™

Catalog No. PIMA543755
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100 μL
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PIMA543755 20 μL
PIMA543754 100 μL
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Catalog No. PIMA543755 Supplier Invitrogen™ Supplier No. MA543755
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Description

Mouse Monoclonal Antibody

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Interferon alpha-2
Applications Western Blot
Classification Monoclonal
Clone D4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene IFNA2
Gene Accession No. P01563
Gene Alias alpha-2a interferon; Ifa2; IFNA; IFN-a; IFNA 2; Ifna2; IFNA2A; IFNA2B; IFNA2C; IFN-alpha 1b; IFN-alpha-1/13; IFN-alpha-2; IFN-alphaA; INFA2; Interferon; interferon alpha 1b; interferon alpha 2; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family, gene 2; interferon alpha-2; Interferon alpha-A; interferon alpha-D; interferon, alpha 2; Interferon-alpha II; leIF A; leIF D; RP11-354P17.2
Gene Symbols IFNA2
Host Species Mouse
Immunogen Cys24-Glu188 (Accession P01563), with N-terminal His and GST Tag.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3440
Target Species Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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