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Invitrogen™ Interferon beta Monoclonal Antibody (C2), Invitrogen™

Catalog No. PIMA543753
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100 μL
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PIMA543753 20 μL
PIMA543752 100 μL
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Catalog No. PIMA543753 Supplier Invitrogen™ Supplier No. MA543753
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Description

Mouse Monoclonal Antibody

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Interferon beta
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Ifnb1
Gene Accession No. P01574
Gene Alias Fibroblast interferon; Ifb; IFF; IFN b; IFN β; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNβ; Interferon; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
Gene Symbols Ifnb1
Host Species Mouse
Immunogen Met22-Asn187.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3456
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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