Invitrogen™ INTS8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120741

Catalog No. PIPA5120741

Description

Positive test controls include: Mouse brain. Immunogen sequence: VTEFSPKLRQ VMLNEMLLLD IHTHEAGTGQ AGERPPSDLI SRVRGYLEMR LPDIPLRQVI AEECVAFMLN WRENEYLTLQ VPAFLLQSNP YVKLGQLLAA TCKELPGPKE SRRTAKDLWE VVVQICSVSS QHKRGNDGRV SLIKQRESTL GIMYRSELLS FIKKLREPLV LTIILSLFVK LHNVREDIVN DITAEHISIW P.

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: INTS8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: INTS8
• Gene Alias: C8orf52; FLJ20530; Int8; integrator complex subunit 8; INTS8; MGC131633; Protein kaonashi-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55656, 72656
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.62 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q75QN2, Q80V86
• Gene Symbols: INTS8
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-800 of human INTS8 (NP_060334.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG