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Invitrogen™ INTU Polyclonal Antibody

Catalog No. PIPA535900
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100 μL
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PIPA535900 100 μL
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Catalog No. PIPA535900 Supplier Invitrogen™ Supplier No. PA535900
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Mouse brain. Predicted reactivity: Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen INTU
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene INTU
Gene Accession No. Q059U7, Q9ULD6
Gene Alias 9230116I04Rik; 9430087H23Rik; homolog of inturned; INT; Intu; Inturned planar cell polarity effector homolog; inturned planar cell polarity effector homolog (Drosophila); inturned planar cell polarity protein; KIAA1284; mKIAA1284; PDZ domain containing 6; PDZ domain-containing protein 6; PDZD6; PDZK6; Protein inturned
Gene Symbols INTU
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human INTU. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27152, 380614
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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