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Invitrogen™ Involucrin Recombinant Rabbit Monoclonal Antibody (JU30-27)
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Catalog No. PIMA541243
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100 μL
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Catalog No. Quantity
PIMA541243 100 μL
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Catalog No. PIMA541243 Supplier Invitrogen™ Supplier No. MA541243
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Description

Rabbit Recombinant Monoclonal Antibody

Involucrin Recombinant Monoclonal Antibody for Western Blot, IHC (P), Flow

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions and is reduced in severe dysplasias of the larynx and cervix. Its gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Involucrin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JU30-27
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IVL
Gene Accession No. P07476, P48998
Gene Alias 1110019C06Rik; involucrin; IVL
Gene Symbols IVL
Host Species Rabbit
Immunogen Synthetic peptide within human involucrin aa 131-180.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3713, 60583
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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