Invitrogen™ INVS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121821

Catalog No. PIPA5121821

Description

INVS Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: INVS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Invs
• Gene Alias: INV; inversin; Inversion of embryo turning homolog; inversion of embryo turning protein; inversion of embryonic turning; INVS; nephrocystin 2; nephrocystin-2; NPH2; NPHP2; RGD1563359
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27130
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q9Y283
• Gene Symbols: Invs
• Immunogen: Recombinant protein Nephronophthisis 2, Infantile. The antigen corresponds to amino acid range 1-237 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG