Invitrogen™ INVS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576584

Catalog No. PIPA576584

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: INVS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Invs
• Gene Alias: INV; inversin; Inversion of embryo turning homolog; inversion of embryo turning protein; inversion of embryonic turning; INVS; nephrocystin 2; nephrocystin-2; NPH2; NPHP2; RGD1563359
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16348, 27130
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O89019, Q9Y283
• Gene Symbols: Invs
• Immunogen: Recombinant fusion protein of human INVS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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