2-Iodoacetamide, 98%, stab. with ca 5-8% water

Manufacturer: Alfa Aesar A1471514

Quantity 25g

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Catalog No. AAA1471514

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    Chemical Identifiers

    CAS 144-48-9
    Molecular Formula ICH2CONH2
    Formula Weight 184.96g/mol
    MDL Number MFCD00008028
    UN Number UN2811
    Beilstein 1739080
    Chemical Name or Material Iodoacetamide, stabilized with ≈5 to 8% water

    Specifications

    Quantity 25g
    CAS 144-48-9
    Assay Percent Range 98%, stabilized with ca 5% water
    Molecular Formula ICH2CONH2
    Formula Weight 184.96g/mol
    MDL Number MFCD00008028
    UN Number UN2811
    Beilstein 1739080
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H301-H315-H319-H317-H335
    Toxic if swallowed.
    Causes skin irritation.
    Causes serious eye irritation.
    May cause an allergic skin reaction.
    May cause respiratory irritation.
    Health Hazard 3 GHS P Statement
    P261-P280-P301+P310-P305+P351+P338-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF SWALLOWED: Immediately call a POISON CENTER
    Recommended Storage 2° to 8°C
    DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
    RTECS Number AC4200000
    TSCA TSCA
    Chemical Name or Material Iodoacetamide, stabilized with ≈5 to 8% water
    Assay 98%

    Description

    Applications
    Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

    Solubility
    Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

    Notes
    Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.

    GHS H Statement
    H301-H315-H319-H317-H335
    Toxic if swallowed.
    Causes skin irritation.
    Causes serious eye irritation.
    May cause an allergic skin reaction.
    May cause respiratory irritation.

    2° to 8°C

    GHS P Statement
    P261-P280-P301+P310-P305+P351+P338-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF SWALLOWED: Immediately call a POISON CENTER

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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