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Invitrogen™ IP3 Receptor 1 Polyclonal Antibody
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Catalog No. PIPA596855
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100 μL
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PIPA596855 100 μL
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Catalog No. PIPA596855 Supplier Invitrogen™ Supplier No. PA596855
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Description

Rabbit Polyclonal Antibody

Positive Samples: HeLa, HT-1080, Mouse kidney, Mouse brain; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein Immunogen sequence: ASNLVIDLIM NASSDRVFHE SILLAIALLE GGNTTIQHSF FCRLTEDKKS EKFFKVFYDR MKVAQQEIKA TVTVNTSDLG NKKKDDEVDR DAPSRKKAKE.

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IP3 Receptor 1
Applications ELISA, Western Blot, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1.94 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Itpr1
Gene Accession No. P11881, Q14643
Gene Alias ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3>R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
Gene Symbols Itpr1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1812-1911 of human IP3R (NP_001365381).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16438, 3708
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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