IPO5 Mouse anti-Human, Mouse, Clone: OTI1C5, liquid, TrueMAB™

Catalog No.	Quantity
50-168-4330	100 μL

Catalog No. 50-168-4330 Supplier OriGene Supplier No. TA811923

Description

Mouse Monoclonal Antibody

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Specifications

• Antigen: IPO5
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1C5
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: IPO5
• Gene Accession No.: O00410, Q8BKC5
• Gene Alias: IMB3, KPNB3, Pse1, RANBP5, imp5
• Gene Symbols: IPO5
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-220 of human IPO5 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3843, 70572
• Target Species: Human, Mouse
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1