IQCB1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-157-0588	100 μL

Catalog No. 50-157-0588 Supplier Bethyl Laboratories, Inc Supplier No. A305499A

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

The nephrocystin proteins comprise a family of five enzymes that commonly interact with p130Cas, proline-rich tyrosine kinases, calmodulin and tensin, indicating that these proteins may participate in a common signaling pathway. Localized to the outer segments and primary cilia of photoreceptor cells, nephrocystin-5 is complexed with RPGR (retinitis pigmentosa GTPase regulator) and interacts directly with calmodulin. Nephrocystin-5 is thought to participate with RPGR in a pathway of ciliary function in the kidey and retina. Mutations in the gene encoding nephrocystin-5 are the primary cause of Senior-Loken syndrome 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

Specifications

• Antigen: IQCB1
• Applications: Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: IQCB1
• Gene Accession No.: Q15051
• Gene Alias: IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ, IQCB1, KIAA0036, NPHP5, OK/SW-cl.85
• Gene Symbols: IQCB1
• Host Species: Rabbit
• Immunogen: Between 548 and 598
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9657
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG