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Invitrogen™ IQGAP1 Polyclonal Antibody
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Catalog No. PIPA596385
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100 μL
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PIPA596385 100 μL
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Catalog No. PIPA596385 Supplier Invitrogen™ Supplier No. PA596385
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELMKLKAQAH AENNEFITWN DIQACVDHVN LVVQEEHERI LAIGLINEAL DEGDAQKTLQ ALQIPAAKLE GVLAEVAQHY QDTLIRAKRE KAQEIQDESA VLWLDEIQGG IWQSNKDTQE AQKFALGIFA INEAVESGDV GKTLSALRSP DVGLYGVIPE CGETYHSDLA EAKKKKLAVG DNNSKWVKHW VKGGYYYYHN LETQEGGWDE PPNFVQNSMQ LSREEIQSSI SGVTAAYNRE QLWLANEGLI T; Positive Samples: A-549, 293T, HepG2, HT-29, HeLa; Cellular Location: Cell membrane.

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IQGAP1
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene IQGAP1
Gene Accession No. P46940, Q9JKF1
Gene Alias AA682088; Cdc42-Rac1 effector protein; D7Ertd237e; D7Ertd257e; DISP2; DISPB; HUMORFA01; IQ motif containing GTPase activating protein 1; IQGAP1; KIAA0051; mKIAA0051; p195; Ras GTPase-activating-like protein IQGAP1; RasGAP-like with IQ motifs; SAR1
Gene Symbols IQGAP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human IQGAP1 (NP_0038611).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29875, 361598, 8826
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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