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IQGAP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572030
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50-157-2030 10 μL
50-157-2029 100 μL
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Catalog No. 50-157-2030 Supplier Bethyl Laboratories, Inc Supplier No. IHC00399T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Dog, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Small-eared galago, African elep

DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.

Specifications

Antigen IQGAP1
Applications Immunofluorescence, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene IQGAP1
Gene Accession No. P46940
Gene Alias IQGAP1; IQ motif containing GTPase activating protein 1; HUMORFA01; KIAA0051; SAR1; p195; RasGAP-like with IQ motifs
Gene Symbols IQGAP1
Host Species Rabbit
Immunogen Between 1 and 50
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8826
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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