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IQGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501733754 Shop All Proteintech Group Inc Products
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50-173-3754 150 μL
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Catalog No. 50-173-3754 Supplier Proteintech Group Inc Supplier No. 221671AP150UL
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Description

Rabbit Polyclonal Antibody

DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.

Specifications

Antigen IQGAP1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IQGAP1
Gene Accession No. P46940, Q9JKF1
Gene Alias HUMORFA01, IQGAP1, KIAA0051, p195, SAR1
Gene Symbols IQGAP1
Host Species Rabbit
Immunogen IQGAP1 Fusion Protein Ag17821
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29875, 8826
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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