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Invitrogen™ IRAK-M Polyclonal Antibody
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Catalog No. PIPA521559
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100 μL
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PIPA521559 100 μL
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Catalog No. PIPA521559 Supplier Invitrogen™ Supplier No. PA521559
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: DDDDK-tagged IRAK3-transfected 293T. Predicted reactivity: Mouse (80%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRAK-M
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene IRAK3
Gene Accession No. Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human IRAK3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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