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Invitrogen™ IRAK-M Polyclonal Antibody
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Catalog No. PIPA586500
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100 μL
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Catalog No. Quantity
PIPA586500 100 μL
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Catalog No. PIPA586500 Supplier Invitrogen™ Supplier No. PA586500
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Description

Rabbit Polyclonal Antibody

Purity is > 95% by SDS-PAGE.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRAK-M
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene IRAK3
Gene Accession No. Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen Synthetic peptide, corresponding to amino acids 500-540 of Human IRAK-M.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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