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Invitrogen™ IRAK4 Monoclonal Antibody (2H9)
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Catalog No. PIMA515883
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100 μL
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Catalog No. Quantity
PIMA515883 100 μL
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Catalog No. PIMA515883 Supplier Invitrogen™ Supplier No. MA515883
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Description

Mouse Monoclonal Antibody

MA5-15883 targets IRAK4 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples. The MA5-15883 immunogen is purified recombinant fragment of human IRAK4 expressed in E. Coli. . MA5-15883 detects IRAK4 which has a predicted molecular weight of approximately 52kDa.

IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways. IRAK-4 interacts with and phosphorylates IRAK-1. IRAK-4-deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRAK4
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2H9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene IRAK4
Gene Accession No. Q8R4K2, Q9NWZ3
Gene Alias 8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64
Gene Symbols IRAK4
Host Species Mouse
Immunogen Purified recombinant fragment of human IRAK4 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 266632, 51135
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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