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Invitrogen™ IREB2 Recombinant Rabbit Monoclonal Antibody (4I4R1)
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Catalog No. FEMA551268
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FEMA551268 100 μL
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Catalog No. FEMA551268 Supplier Invitrogen™ Supplier No. MA551268
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: SLEAPDSVLF PWDLKSTYIR CPSFFDKLTK EPIALQAIEN AHVLLYLGDS VTTDHISPAG SIARNSAAAK YLTNRGLTPR EFNSYGARRG NDAVMTRGTF ANIKLFNKFI GKPAPKTIHF PSGQTLDVFE AAELYQKEGI PLIILAGKKY GSGNSRDWAA KGPYLLGVKA VLAESYEKIH KDHLIGIGIA PLQFLPGENA DSLGLSGRET FSLTFPEELS PGITLNIQTS TGKVFSVIAS FEDDVEITLY KHGGLLNFVA RKFS.

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
TRUSTED_SUSTAINABILITY

Specifications

Antigen IREB2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 4I4R1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Gene IREB2
Gene Accession No. P48200, Q62751, Q811J3
Gene Alias ACO3; D9Ertd85e; FLJ23381; im:7153062; Ireb2; IRE-BP 2; IREBP2; Iron regulatory protein 2; iron responsive element binding protein 2; iron-regulatory protein 2; iron-responsive element binding protein 2; iron-responsive element-binding protein 2; Iron-responsive element-binding protein 2-like protein; IRP2; IRP2AD
Gene Symbols IREB2
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3658, 64602, 64831
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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