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Invitrogen™ IRF1 Recombinant Rabbit Monoclonal Antibody (2F9)
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Catalog No. PIMA524849
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PIMA524849 100 μL
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Catalog No. PIMA524849 Supplier Invitrogen™ Supplier No. MA524849
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. Purity is > 95% by SDS-PAGE.

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression. Diseases associated with IRF1 include gastric cancer, somatic and lung cancer.
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Specifications

Antigen IRF1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone 2F9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene IRF1
Gene Accession No. P10914, P15314, P23570
Gene Alias AU020929; Interferon regulatory factor 1; interferon regulatory factor 1 isoform +I9; interferon regulatory factor 1 isoform d78; interferon regulatory factor 1 isoform delta4; interferon regulatory factor 1 isoform delta7; IRF1; IRF-1; MAR
Gene Symbols IRF1
Host Species Rabbit
Immunogen Synthetic peptide of human IRF1 (aa 126-325).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16362, 24508, 3659
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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