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Invitrogen™ IRF4 Monoclonal Antibody (3E4), Brilliant Violet™ 650, eBioscience™, Invitrogen™

Catalog No. 416985880
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41-698-5880 25 μg
41-698-5882 100 μg
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Catalog No. 41-698-5880 Supplier Invitrogen™ Supplier No. 416985880
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Rat Monoclonal Antibody

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF4
Applications Flow Cytometry
Classification Monoclonal
Clone 3E4
Concentration 0.2 mg/mL
Conjugate Brilliant Violet 650
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene IRF4
Gene Accession No. Q15306, Q64287
Gene Alias AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Gene Symbols IRF4
Host Species Rat
Purification Method Affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16364, 3662
Target Species Human, Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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