IRF4 Mouse anti-Human, Porcine, Rat, Clone: 1A12D5, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 664511IG150UL

Catalog No. 50-173-6877

Description

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.

Specifications

• Antigen: IRF4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15306
• Gene Symbols: Irf4
• Immunogen: IRF4 Fusion Protein Ag25203
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 1A12D5
• Conjugate: Unconjugated
• Gene: IRF4
• Gene Alias: interferon regulatory factor 4, IRF 4, IRF4, LSIRF, Multiple myeloma oncogene 1, MUM1, NF EM5
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100144625, 291100, 3662
• Content And Storage: -20°C
• Form: Liquid